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    3. Are you choosing the best Isotype Control?

      來源: BioXcell   2020-12-22   訪問量:301評論(0)

      Just Pure Antibodies

      Isotype control

      CHOOSING AND USING ISOTYPE CONTROLS FOR IN VIVO EXPERIMENTS

      Selecting and using the correct isotype control antibody is an essential part of all in vivo experiments. These antibodies are used as a negative control – they match the exact host species, isotype, and subclass of the primary targeting antibody, but have no specificity to proteins present in the target organism or species. Isotype control antibodies are designed to be non-binding in in vivoanimal models but retain all the non-specific characteristics of the primary antibodies used in an experiment. For the convenience of our customers, we have indicated the proper isotype control for each of our primary antibodies, which can be found on each product page. We have also compiled a comprehensive list of Bio X Cell’s isotype control antibodies which are all well documented for both in vivo and in vitro research.

      RSV

      Mucosal Microenvironment Matters: A Role for Neutrophilic Inflammation in Viral Predisposition

      Why do certain people become sick after exposure to a virus while others do not? Although some evidence points to duration of exposure or antibodies from previous infections, the biological underpinnings of variable transmission remain incompletely understood. Studying first human volunteers and then validating their findings with mouse models, researchers used Bio X Cell’s anti-mouse Ly6G (clone 1A8) and anti-mouse CD8 (clone YTS169.4)antibodies to help define neutrophilic inflammation as an important component of susceptibility to respiratory infections. These findings have implications not only for RSV but for other viruses with long incubation periods as well, including SARS-CoV-2.

      BioFund_Giving back

      A Year of Giving Back - Bio X Cell Fund 2020

      Bio X Cell has a long-standing tradition of giving back to the community through charitable giving and community participation and service. Making a difference in our community – at the local, national, and global level gives meaning to the work we do at Bio X Cell and fulfills us as individuals. 2020 presented unique challenges to many people and organizations as a direct result of the COVID-19 crisis. This year, BioFund set aside $275,000 to support organizations doing important work in our immediate community and beyond. These organizations included nonprofits providing essential services such as Willing Hands, Meals on Wheels, and more. We also sponsored American Red Cross of Northern New England COVID-19 antibody testing initiative and covered the cost of testing all blood products collected in Grafton County for four months.



      BioXcell   商家主頁

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      聯系人:BioXcell
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